Our labs and collaborative publications since 2019

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Kasanga, E.A. Han, Y., Shifflet, M.K., Navarrete, W., McManus, R., Parry, C., Barahona, A., Nejtek, V.A., Manfredsson, F.P., Kordower, J.H., Richardson, Salvatore, M.F.   Nigral-specific increase in ser31 phosphorylation compensates for tyrosine hydroxylase protein and nigrostriatal neuron loss: Implications for delaying parkinsonian signs. Exp Neurol 368: 114509, 2023. PMID 37634696

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Kasanga, E.A., Han, Y., Navarrete, W., McManus, R., Shifflet, M.K., Parry, C., Barahona, A., Manfredsson, F.P., Nejtek, V.A., Richardson, J.R., Salvatore, M.F.  Differential expression of RET and GDNF family receptor, GFR-a1, between striatum and substantia nigra following nigrostriatal lesion: a case for diminished GDNF signaling.  Exp Neurol. 366: 114435, 2023. PMID 37178997

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Salvatore, M.F., Soto, I., Kasanga, E.A., James, R., Shifflet, M.K., Doshier, K., Little, J.T., John, J., Alphonso, H.M., Cunningham, J.T., Nejtek, V.A.  Establishing equivalent aerobic exercise parameters between early-stage Parkinson's disease and Pink1 knockout rats.  J Parkinson's Dis. 12: 1897-1915, 2022. PMID 35754287

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Salvatore, M.F., Kasanga, E.A., Kelly,P., Venable, K.E. Cantu, M.A., McInnis T.R., Terrebonne, J., Lanza, K., Meadows, S.M., Centner, A., Bishop, C.,  Ingram, D.K. Modulation of nigral dopamine signaling mitigates parkinsonian signs of aging: evidence from intervention with calorie restriction or inhibition of dopamine uptake.  GeroScience. 45: 45-63, 2023 PMID 35635679

 

Kasanga, E.A., Little J., McInnis, T.R., Bugnariu, N., Cunningham, J.T., Salvatore, M.F. Cardiovascular Metrics Associated With Prevention of Aging-Related Parkinsonian Signs Following Exercise Intervention in Sedentary Older Rats. Front Aging Neurosci 13:775355, 2021. PMID 34975456.

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Nejtek, V.A., James, R.N., Salvatore, M.F., Alphonso, H.M., Boehm, G.W. Premature cognitive decline in specific domains found in young veterans with mTBI coincide with elder normative scores and advanced-age subjects with early-stage Parkinson’s disease. PLoS ONE 16(11):e0258851, 2021. PMID 34788310.

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Salvatore, M.F., Soto, I., Alphonso, H., Cunningham, R., James, R., Nejtek, V.A. Is there a neurobiological rationale for the utility of the Iowa Gambling Task in Parkinson’s Disease?  J Parkinson’s Dis. 11(2): 405-419, 2021. PMID 33361612.

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Kasanga, E.A., Owens, C.L., Cantu, M.A., Richard, A.D., Davis, R.W., McDivitt, L.M., Blancher, B., Pruett, B.S., Tan, C., Gajewski,A., Manfredsson, F.P., Nejtek, V.A., Salvatore, M.F.  GFR-alpha 1 expression in substantia nigra increases bilaterally following unilateral strital GDNF in aged rats and attenuates nigral tyrosine hydroxylase loss following 6-OHDA nigrostriatal lesion.  ACS Chem Neurosci 10: 4237-4249, 2019. PMID: 31538765.

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Churchill, M.J., Cantu, M.A., Kasanga, E.A., Moore, C., Salvatore, M.F., Meshul, C.K.  Glatiramer acetate reverses motor dysfunction and the decrease in tyrosine hydroxylase levels in a mouse model of Parkinson's disease.  Neuroscience 414: 8-27, 2019.  PMID 31220543.

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Salvatore, M.F., McInnis, T.R., Cantu, M.A., Apple, D.M., Pruett, B.S.  Tyrosine hydroxylase inhibition in substantia nigra decreases movement frequency.  Mol Neurobiol 56: 2728-2740, 2019. PMID: 30056575. 

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