Our labs and collaborative publications since 2021

 

Doshier, K., Ryals, A.J., Nejtek, V.A., Salvatore, M.F., Lisk, J. Eye movements during the Iowa Gambling Task in Parkinson's disease: a brief report.  Front Psychol 16: 1478500, 2025.

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Kasanga, E.A., Soto, I., Centner, A., McManus, R., Shifflet, M.K., Navarrete, W., Han, Y., Lisk, J., Ehrhardt, T., Wheeler, K., Mhatre-Winters, I., Richardson, J.R., Bishop, C., Nejtek, V.A., Salvatore, M.F.  Moderate intensity aerobic exercise alleviates motor deficits in 6-OHDA lesioned rats and reduces serum levels of biomarkers of Parkinson's disease severity without recovery of striatal dopamine or tyrosine hydroxylase. Exp Neurol 379: 114875, 2024.

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Soto, I., Nejtek, V.A., Siderovski, D.P., Salvatore, M.F.  PINK1 knockout rats show premotor cognitive deficits measured through a complex maze. Front Neurosci 18: 1390215, 2024.

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Soto, I., McManus, R., Navarrete, W., Kasanga, E.A., Doshier, K., Nejtek, V.A., Salvatore, M.F.  Aging accelerates locomotor decline in PINK1 knockout rats in association with decreased nigral, but not striatal, dopamine and tyrosine hydroxylase expression. Exp Neurol  376, 114771, 2024.  PMID 38580154

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Salvatore, M.F.  Dopamine signaling in substantia nigra and its impact on locomotor function; not a new concept, but neglected reality.  Int J Mol Sci  25: 1131, 2024. PMID 38256204

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Kasanga, E.A. Han, Y., Shifflet, M.K., Navarrete, W., McManus, R., Parry, C., Barahona, A., Nejtek, V.A., Manfredsson, F.P., Kordower, J.H., Richardson, Salvatore, M.F.   Nigral-specific increase in ser31 phosphorylation compensates for tyrosine hydroxylase protein and nigrostriatal neuron loss: Implications for delaying parkinsonian signs. Exp Neurol 368: 114509, 2023. PMID 37634696

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Kasanga, E.A., Han, Y., Navarrete, W., McManus, R., Shifflet, M.K., Parry, C., Barahona, A., Manfredsson, F.P., Nejtek, V.A., Richardson, J.R., Salvatore, M.F.  Differential expression of RET and GDNF family receptor, GFR-a1, between striatum and substantia nigra following nigrostriatal lesion: a case for diminished GDNF signaling.  Exp Neurol. 366: 114435, 2023. PMID 37178997

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Salvatore, M.F., Soto, I., Kasanga, E.A., James, R., Shifflet, M.K., Doshier, K., Little, J.T., John, J., Alphonso, H.M., Cunningham, J.T., Nejtek, V.A.  Establishing equivalent aerobic exercise parameters between early-stage Parkinson's disease and Pink1 knockout rats.  J Parkinson's Dis. 12: 1897-1915, 2022. PMID 35754287

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Salvatore, M.F., Kasanga, E.A., Kelly,P., Venable, K.E. Cantu, M.A., McInnis T.R., Terrebonne, J., Lanza, K., Meadows, S.M., Centner, A., Bishop, C.,  Ingram, D.K. Modulation of nigral dopamine signaling mitigates parkinsonian signs of aging: evidence from intervention with calorie restriction or inhibition of dopamine uptake.  GeroScience. 45: 45-63, 2023 PMID 35635679

 

Kasanga, E.A., Little J., McInnis, T.R., Bugnariu, N., Cunningham, J.T., Salvatore, M.F. Cardiovascular Metrics Associated With Prevention of Aging-Related Parkinsonian Signs Following Exercise Intervention in Sedentary Older Rats. Front Aging Neurosci 13:775355, 2021. PMID 34975456.

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Nejtek, V.A., James, R.N., Salvatore, M.F., Alphonso, H.M., Boehm, G.W. Premature cognitive decline in specific domains found in young veterans with mTBI coincide with elder normative scores and advanced-age subjects with early-stage Parkinson’s disease. PLoS ONE 16(11):e0258851, 2021. PMID 34788310.

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Salvatore, M.F., Soto, I., Alphonso, H., Cunningham, R., James, R., Nejtek, V.A. Is there a neurobiological rationale for the utility of the Iowa Gambling Task in Parkinson’s Disease?  J Parkinson’s Dis. 11(2): 405-419, 2021. PMID 33361612.

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